منابع مشابه
Novel Antithrombotic Drugs on the Horizon
Diseases associated with arterial thrombosis or venous thrombosis are leading causes of mortality and morbidity globally. Since the 1930s, antithrombotic therapy has been the cornerstone of medical therapy for thrombotic diseases. However, the success of antithrombotic therapy has come at the cost of one of the most dreaded iatrogenic complications—bleeding. Recently, new evidence has emerged o...
متن کاملStatins as antithrombotic drugs.
Statins as Antithrombotic Drugs Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2013 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.112.145334 2013;127:251-257 Circulation. http://circ.ahajournals.org/content/127/2/251 World Wide Web at: The online ve...
متن کاملNew antithrombotic drugs.
Thrombosis, both venous and arterial, is a major cause of morbidity and mortality worldwide. Consequently, there is an ongoing search for new antithrombotic drugs, particularly novel antiplatelet agents and anticoagulants. A better understanding of the biochemical pathways involved in platelet activation and coagulation and of the links between these systems and the impact of thrombosis on infl...
متن کاملThe influence of new antithrombotic drugs on regional anesthesia.
PURPOSE OF REVIEW Antithrombotic drugs are known to increase the risk of spinal epidural hematoma after neuraxial blockade. During the last few years, several new anticoagulants have been introduced, some of them more potent than the drugs currently available. More potency, however, may also indicate a higher risk of bleeding. RECENT FINDINGS Case series from the last few years indicate that ...
متن کاملNew Drugs on the Horizon: Matrix Metalloproteinase Inhibitors.
Matrix metalloproteinases (MMPs) are a family of enzymes involved in a number of normal cellular processes, such as regulation of endometrial growth and menstruation, and abnormal processes, such as tumor growth, invasion, and metastasis. There are now 18 distinct enzymes that fall into three functional classifications based on their substrate target: collagenases which degrade fibrillar collag...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2017
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.117.312012